Cancer Over-expressed Receptors as Targets for PET Molecular Imaging
 |
|
Описание:
Positron Emission Tomography (PET) is a nuclear medicine imaging technology which allows for four-dimensional, quantitative determination of the distribution of labeled biological compounds within the human body. The high sensitivity of PET and the low concentration of the tracers used, allow quantitative visualization of low capacity biochemical systems such as receptors. Epidermal growth factor receptor (EGFR) is involved in proliferation, cell movement, cell survival and differentiation of both normal and malignant cells. EGFR over-expression has been detected in a variety of malignant epithelial tumors. Androgen Receptor (AR) plays a critical role in initiation and growth of prostate cancer cells. Nearly 80-90% of prostate cancers are dependent on androgen at initial diagnosis. While EGFR and AR are established targets for treatment, the clinical outcome in most cases is suboptimal. Development of suitable labeled biomarkers that bind to the EGFR or to the AR may allow the mapping...Похожие книги
 | Saw Palmetto for Men & Women: Herbal Healing for the Prostate, Urinary Tract, Immune System and More Автор: David Winston Год: 1999 |
 | Hormone Therapy in Breast and Prostate Cancer (Cancer Drug Discovery and Development) Автор: V. Craig Jordan, B.J.A. Furr Год: 2002 |
 | Hormone therapy in breast and prostate cancer Автор: V Craig Jordan,B J A Furr Год: 2002 |
| Adult Reconstruction Автор: Martin I. Resnick Год: 2000 |
 | La prostata : Todo lo que necesita saber sobre la glandula masculina Автор: Yosh Taguchi Год: 2004 |
 | Masculinity Versus Castration: On the Way to Fighting Prostate Cancer Автор: Santiago Vilas Год: 2004 |