From melanocytes to melanoma: the progression to malignancy

From melanocytes to melanoma: the progression to malignancy
Автор
 
Год
 
Страниц
 
673
ISBN
 
ISBN10:1588294595;ISBN10:159259994X;ISBN13:9781592599943;ISBN13:9781588294593
Издатель
 
Humana Press

Описание:

Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.

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