Functional Genomics. Methods and Protocols

Functional Genomics. Methods and Protocols
Автор
 
Год
 
Страниц
 
272
ISBN
 
ISBN10:1588292916
Издатель
 
Humana Press

Описание:

This collection of robust, readily reproducible methods for microarray-based studies includes expert guidance in the optimal data analysis and informatics. On the methods side are proven techniques for monitoring subcellular RNA localization en masse, for mapping chromosomes at the resolution of a single gene, and for surveying the steady-state genome-wide distribution of DNA binding proteins in vivo. For those workers dealing with massive data sets, the book discusses the methodological aspects of data analysis and informatics in the design of microarray experiments, the choice of test statistic, and the assessment of observational significance, data reduction, and clustering.

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