Inflammatory Bowel Disease
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Описание:
Inflammatory bowel disease (IBD) comprises a group of idiopathic diseases of the intestine characterized by chronic inflammation of the bowel with periods of exacerbation and remission. The two major categories of IBD are ulcerative colitis and Crohn?s disease. In their classical forms, they differ both clinically and histologically but it is still uncertain whether they are distinct diseases. Although the exact cause of IBD remains undetermined, the condition appears to be related to a combination of genetic and environmental factors that result in aberrant activation of the mucosal immune system. Whilst chemotherapeutic treatments are usually effective in most patients in maintaining prolonged remission and decreasing the length of active disease periods, such treatments have side effects and a significant number of people still require surgery. This important book draws together four fundamental strands in IBD research: genetics, bacteriology, epithelial biology and...Похожие книги
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