Keratinocyte Growth Factor

Keratinocyte Growth Factor
Автор
 
Год
 
Страниц
 
16

Описание:

Keratinocyte growth factor (KGF) is a member of the fibroblast growth factor family whose specificity for epithelial tissues is a consequence of the restricted expression of its receptor, KGF receptor (also known as FGFR2IIIb), on epithelial cells. KGF is typically expressed in stromal or mesenchymal cells adjacent to epithelia and is thought to be an endogenous paracrine regulator of epithelial cell growth, differentiation, and repair. Administration of recombinant human KGF (rHuKGF) has growth, differentiating, and cytoprotective effects on epithelium in animals and humans, and may be a potential therapeutic agent for a variety of conditions involving epithelial injury and/or inflammation. Clinical studies in cancer patients provide evidence that rHuKGF is therapeutically effective in ameliorating chemoradiotherapy-induced oral epithelial injury.

Похожие книги

Child Injury. Injury Epidemiology in Palestinian School-childrenChild Injury. Injury Epidemiology in Palestinian School-children
Год: 2011
EPIC (Form Factor)EPIC (Form Factor)
Год: 2011
Computer form FactorComputer form Factor
Год: 2011
Endothelium-derived Relaxing FactorEndothelium-derived Relaxing Factor
Год: 2011
Anti-apoptotic and Pro-inflammatory Signaling in Cancer Cells. Status and Modulation by Chemotherapeutic DrugsAnti-apoptotic and Pro-inflammatory Signaling in Cancer Cells. Status and Modulation by Chemotherapeutic Drugs
Год: 2011
Prevention of Infertility and Complications in Women: A Comprehensive Guide to the Preservation of Female Reproductive HealthPrevention of Infertility and Complications in Women: A Comprehensive Guide to the Preservation of Female Reproductive Health
Автор: Godwin I. Meniru
Год: 2003