Long-lasting stress-induced changes in neuronal alternative splicing

Long-lasting stress-induced changes in neuronal alternative splicing
Автор
 
Год
 
Страниц
 
100
ISBN
 
9783639147162
Категория
 
Новые поступления
Искать в интернет библиотекахКупить

Описание:

Ample information suggests multileveled relationships between long-term psychological stress responses and alternative splicing– the process which yields different mRNAs from the same gene. However, the nature of these relationships remains unclear. Eran Meshorer studied the stress-induced changes in alternative splicing at Hermona Soreq’s lab and shed light on the molecular pathways that lead to such responses. Meshorer focused on a particular mRNA - acetylcholinesterase (AChE), which is neuronally-expressed, stress-responsive, and yields alternatively spliced products, thus serving as an adequate model for this purpose. The book begins with an introduction covering the general areas of stress responses, their long-term consequences, the mechanism of splicing and alternative splicing, neuritic translocation of mRNAs and highlights the AChE gene and its protein products as putative mediators of such long-term consequences. The results section depicts 3 works describing 3’ and 5’...

Похожие книги

Integrating the Visual ArtsIntegrating the Visual Arts
Автор: Jill Palacki
Год: 2010
Psychiatric and Neurologic Aspects of WarPsychiatric and Neurologic Aspects of War
Автор: Jack D. Barchas
Год: 2010