Trace Quantitative Analysis by Mass Spectrometry
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Описание:
This book is devoted to the use of mass spectrometry in quantitative measurements of amounts of target (known) chemical compounds present at trace levels in complex matrices, such as drugs and their metabolites in body fluids, pesticide residues in foodstuffs, contaminants in drinking water, etc. Such demanding measurements, defined as 1 part in 10 6– 10 12 , involve the use of a wide range of apparatus and of experimental procedures and methods of data evaluation, all of which must be utilized properly if reliable estimates of chemical concentrations and their associated uncertainties are to be obtained. While this is true of any chemical analysis, modern advances in trace–level analysis are critically dependent on developments in mass spectrometry. The approach adopted throughout the book is to emphasize the fundamentals underlying the scientific instruments andmethodologies, illustrated by historically important developments and more recent innovations....Похожие книги
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